Directed organ donation: is the donor the owner?

Donor sepsis is not a contraindication to cadaveric organ donation.

Systemic donor infection is regarded as being an absolute contraindication to cadaveric organ donation for transplantation. This is largely due to fear of transmitting pathogenic organisms to the immunosuppressed recipient. However, due to the current shortage of organs available for transplantation, clinicians are faced with the option of using organs from 'non-ideal' donors, such as those pat...

The dead-donor rule and the future of organ donation.

1287 cular risks of rosiglitazone led to a major change in FDA policy regarding the approval of all new diabetes drugs. From a cardiovascular perspective, rosiglitazone, saxagliptin, and alogliptin appear to be relatively safe. It is disappointing, however, that neither intensive glycemic control nor the use of specific diabetes medications is associated with any suggestion of cardiovascular be...

Is altruistic-directed living unrelated organ donation a legal fiction?

activity in porcine septic shock. Anaesth Intensive Care 2007; 35: 911–919 25. Matson JR, Zydney AR, Honore PM. Blood filtration: new opportunities and the implications on system biology. Crit Care Resuc 2004; 6: 209–218 26. Palevsky PM, Zhang JH, O’Connor TZ et al. Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 2008; 359: 7–20 27. Ronco C, Honore P...

Controversies in organ donation: the altruistic living donor.

Organ donation after circulatory death: the forgotten donor?

Donation after circulatory death (DCD) can be performed on neurologically intact donors who do not fulfill neurologic or brain death criteria before circulatory arrest. This commentary focuses on the most controversial donor-related issues anticipated from mandatory implementation of DCD for imminent or cardiac death in hospitals across the USA. We conducted a nonstructured review of selected p...